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Immuno-oncology Program (Chimeron Bio)
- Development stage
- Preclinical
- Lead developer
- Chimeron Bio
- Modality
- Gene Therapies, Nanoparticles → Drug Delivery Systems, RNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Injection
01
Overview
Chimeron Bio's Immuno-oncology Program is an in vivo gene therapy approach designed to modulate the tumor immune microenvironment (TIME) to restore anti-tumor immune surveillance. The program utilizes the company's proprietary MultiPlex RNA delivery platform, which is based on 'Chaomer' technology—self-assembling RNA nanoparticles. This platform enables the coordinated delivery and expression of multiple genes targeting various immune pathways simultaneously. The therapy is designed to provide weeks-long therapeutic activity from a single administration, featuring precise targeting and enhanced cellular uptake to drive the elimination of cancer cells while potentially overcoming the limitations of traditional systemic immunotherapies.
- Other names
- MultiPlex Immuno-oncology ProgramChimeron Bio Immuno-oncology Program
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