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ImmunoExo + CPP-EGF

Development stage: Unknown
Lead developer: TIMEBIO
Modality: Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Peptides, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration: Topical

Overview

ImmunoExo + CPP-EGF is a regenerative therapeutic candidate developed by TIMEBIO for the treatment of thermal burns and impaired wound healing. The product is a combination of immunomodulatory exosomes (ImmunoExo) and a fusion protein consisting of a cell-penetrating peptide (CPP) linked to epidermal growth factor (EGF). The mechanism of action involves the activation of the epidermal growth factor receptor (EGFR) signaling pathway to promote cell proliferation, migration, and tissue repair, while the exosome component provides an anti-inflammatory and pro-regenerative environment. The drug is currently in Phase 1 clinical development.

Other names: Burn/Wound Regeneration TherapyImmunoExo-CPP-EGF

Targets

EGFR T790M (Epidermal growth factor receptor T790M mutant)

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