Drug intelligence / Profile preview

immunoglobulins + lactoferrin

Development stage
Preclinical
Lead developer
All G
Modality
Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

This is a combination of immunoglobulins (antibodies) and lactoferrin, both naturally occurring proteins with roles in immune defense. Immunoglobulins are key components of the adaptive immune system, neutralizing pathogens and facilitating their clearance. Lactoferrin is an iron-binding glycoprotein found in milk and other secretions, known for its antimicrobial, antiviral, anti-inflammatory, and immunomodulatory properties. The combination aims to enhance host immunity by leveraging the pathogen-neutralizing effects of antibodies alongside lactoferrin’s ability to sequester iron (limiting microbial growth), modulate inflammatory responses, block viral entry into cells (including via ACE2 or HSPG receptors), and support gut health. This combination may be used as a dietary supplement or adjunctive therapy for infectious diseases or immune support[1][4][6].

02

Targets

LRP1 (Prolow-density lipoprotein receptor-related protein 1)ACE2 (Angiotensin-converting enzyme 2)HSPG (Basement membrane-specific heparan sulfate proteoglycan core protein (perlecan))

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