Drug intelligence / Profile preview

Infanrix hexa + Menitorix + Synflorix

Development stage
Unknown
Lead developer
GSK
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

This drug entry refers to a pediatric vaccination regimen developed by **GSK**, involving the co-administration of **Infanrix hexa**, **Menitorix**, and a **pneumococcal conjugate vaccine** (specifically **Synflorix**, also known as GSK1024850A). Infanrix hexa is a hexavalent vaccine providing active immunization against diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis, and Haemophilus influenzae type b (Hib). Menitorix is a combined vaccine targeting Hib and Neisseria meningitidis serogroup C. Synflorix is a decavalent vaccine targeting ten serotypes of Streptococcus pneumoniae. This combination is used in clinical trials (e.g., NCT00707733) to evaluate the long-term persistence of antibodies against meningococcal, Hib, pneumococcal, and hepatitis B antigens in children who have completed their primary and booster vaccination series.

Brand names
Infanrix hexaMenitorixSynflorix
Other names
Infanrix hexa-GlaxoSmithKline-meningococcal meningitis-Haemophilus influenzae type b infection-pneumococcal infection-hepatitis BDTPa-HBV-IPV/Hib + Hib-MenC + PCV10
02

Targets

PD (Protein D)CPS (Streptococcus pneumoniae capsular polysaccharide)HBsAg (Hepatitis B surface antigen)Diphtheria toxinPV3 (Sabin) (Poliovirus type 3 antigen)Neisseria meningitidis group C capsular polysaccharideTT (Tetanus toxoid)

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