Drug intelligence / Profile preview

influenza a (h1n1) 2009 pandemic monovalent vaccine (without adjuvant)

Development stage
Unknown
Lead developer
GSK
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

**Influenza A (H1N1) 2009 Pandemic Monovalent Vaccine (Without Adjuvant)** is an inactivated, split-virion, monovalent influenza vaccine indicated for active immunization against the 2009 pandemic H1N1 influenza strain. The vaccine contains 15 µg hemagglutinin per 0.5 mL dose from the A/California/7/2009 (H1N1)v-like strain and is produced by propagating virus in embryonated hens' eggs, inactivating with ultraviolet and formaldehyde, and disrupting with sodium deoxycholate. Designed specifically for pandemic response, it does not contain an adjuvant and is distinct from seasonal influenza vaccines. Its mechanism is to induce immunity through presentation of influenza viral antigens to elicit a humoral immune response (antibody-mediated protection) against the H1N1 virus[1][2][3][4][5].

Brand names
FluviralInfluenza A (H1N1) 2009 Monovalent Vaccine (Without Adjuvant)
Other names
pandemic influenza A (H1N1) vaccine non-adjuvantedinfluenza A/California/7/2009 (H1N1)v-like virus vaccinesplit-virus H1N1 vaccine
02

Targets

HA (Hemagglutinin)

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