Drug intelligence / Profile preview

influenza vaccine (Advax adjuvanted)

Development stage
Approved
Lead developer
Vaxine
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Influenza vaccine (Advax adjuvanted) is a recombinant protein subunit vaccine developed by Vaxine for the prevention of seasonal influenza. The vaccine candidate is composed of recombinant hemagglutinin (rHA) antigens derived from seasonal influenza strains, formulated with Vaxine's proprietary Advax adjuvant. Advax is a unique adjuvant platform based on delta-inulin, a naturally occurring polysaccharide, which is designed to enhance both humoral (antibody) and cellular (T-cell) immune responses. Unlike traditional adjuvants that may cause significant local inflammation, Advax is intended to provide a potent immune boost with a favorable safety and tolerability profile. The vaccine is currently in Phase 2 clinical development, aiming to provide broad and durable protection against circulating influenza A and B viruses.

Brand names
recombinant influenza hemagglutinin + Advax2
Other names
Advax-adjuvanted recombinant influenza vaccineAdvax-adjuvanted seasonal influenza vaccineAdvax-adjuvanted recombinant hemagglutinin vaccine
02

Targets

CD209 (Dendritic cell-specific intercellular adhesion Molecule-3-Grabbing non-integrin)HA (Hemagglutinin)

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