influenza virus quadrivalent vaccine, inactivated

**Influenza virus quadrivalent vaccine, inactivated** is the 2018-2019 seasonal formulation of **Fluzone Quadrivalent**, an egg-derived, split-virion inactivated influenza vaccine manufactured by Sanofi. It contains antigens from two influenza A strains and two influenza B lineages, principally hemagglutinin with smaller amounts of neuraminidase. Intramuscular vaccination induces strain-directed humoral immune responses, including hemagglutination-inhibition and neuraminidase-inhibition antibodies, to prevent influenza caused by vaccine-matched viruses. The licensed unadjuvanted vaccine was evaluated in NIAID-sponsored Phase 1 study NCT03945825 alone or with investigational AF03 or Advax-CpG55.2 adjuvants in healthy adults. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03945825))

Brand names

Fluzone Quadrivalent

Other names

Influenza Virus Quadrivalent Inactivated Vaccinequadrivalent inactivated influenza vaccinequadrivalent influenza vaccineIIV4IIV-4IIV 4