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influenza virus vaccine (2007-2008 season)

Development stage
Approved
Lead developer
Sanofi Pasteur
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular, Intranasal
01

Overview

The influenza virus vaccine for the 2007-2008 Northern Hemisphere season was a trivalent formulation designed to provide protection against the three most prevalent circulating strains of the influenza virus during that period. As recommended by the World Health Organization (WHO) and the FDA's Vaccines and Related Biological Products Advisory Committee (VRBPAC), the formulation included an A/Solomon Islands/3/2006 (H1N1)-like virus, an A/Wisconsin/67/2005 (H3N2)-like virus, and a B/Malaysia/2506/2004-like virus. These vaccines work by inducing neutralizing antibodies against the viral surface glycoproteins, hemagglutinin and neuraminidase, thereby preventing viral entry and release from host cells. Multiple manufacturers produced various forms of the vaccine, including inactivated split-virion, subunit, and live-attenuated intranasal formulations.

Brand names
FluzoneFluarixFluvirinAfluriaFluLavalFluMist
Other names
2007-2008 seasonal influenza vaccineTrivalent influenza vaccine 2007-2008influenza virus vaccine
02

Targets

HA (Hemagglutinin)Neuraminidase

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