Drug intelligence / Profile preview

insulin detemir + insulin lispro

Development stage
Phase 2
Lead developer
Novo Nordisk
Modality
Small Molecules, Recombinant Proteins and Enzymes
Administration
Subcutaneous
01

Overview

This is a combination therapy using two different types of insulin. Insulin detemir (Levemir) is a long-acting insulin that provides basal insulin coverage for up to 24 hours. Insulin lispro (Humalog) is a rapid-acting insulin that starts working within 15 minutes and provides mealtime coverage. When used together, they provide comprehensive glycemic control for patients with diabetes mellitus. Both insulins work by binding to insulin receptors, activating tyrosine kinase activity, and regulating glucose transport and metabolism, but they have different onset times and durations of action due to their unique molecular modifications.

02

Targets

IGF-1R (Insulin-like growth factor 1 receptor)INSR (Insulin receptor)

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