Drug intelligence / Profile preview

insulin detemir + insulin lispro

Development stage
Unknown
Lead developer
Novo Nordisk
Modality
Recombinant Proteins and Enzymes, Small Molecules
Administration
Subcutaneous
01

Overview

This is a combination therapy using two different types of insulin. Insulin detemir (Levemir) is a long-acting insulin that provides basal insulin coverage for up to 24 hours. Insulin lispro (Humalog) is a rapid-acting insulin that starts working within 15 minutes and provides mealtime coverage. When used together, they provide comprehensive glycemic control for patients with diabetes mellitus. Both insulins work by binding to insulin receptors, activating tyrosine kinase activity, and regulating glucose transport and metabolism, but they have different onset times and durations of action due to their unique molecular modifications.

02

Targets

INSR (Insulin receptor)IGF-1R (Insulin-like growth factor 1 receptor)

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