insulin glargine + regular human insulin

This is a combination of two insulins—insulin glargine and regular human insulin—used for the management of diabetes mellitus. Insulin glargine is a long-acting recombinant human insulin analog that provides basal (background) glucose control, typically lasting up to 24 hours with no pronounced peak. Regular human insulin is a short-acting form of recombinant human insulin used to control blood sugar spikes around meals. The combination aims to mimic physiological insulin secretion by providing both basal and prandial (mealtime) coverage, improving glycemic control in patients with type 1 or type 2 diabetes who require both types of action. Both components act as agonists at the insulin receptor, promoting glucose uptake into tissues, inhibiting hepatic glucose production, suppressing lipolysis and proteolysis, and enhancing protein synthesis[1][3][7].

Brand names

Lantus + generic human insulin

Other names

insulin glargine plus human insulin