Drug intelligence / Profile preview

insulin lispro mix25 (Eli Lilly and Company)

Development stage
Unknown
Lead developer
Eli Lilly
Modality
Peptides
Administration
Subcutaneous
01

Overview

Insulin lispro mix25 is a premixed insulin analog formulation containing 25% insulin lispro (a rapid-acting insulin) and 75% insulin lispro protamine suspension (an intermediate-acting insulin). Developed by Eli Lilly and Company and marketed under brand names such as Humalog Mix25 or Humalog Mix 75/25, it is indicated for the treatment of patients with diabetes mellitus who require insulin for the maintenance of glucose homeostasis. The rapid-acting component provides quick onset to cover mealtime glucose excursions, while the protamine-bound component extends the duration of action to provide basal insulin coverage. It is administered subcutaneously, typically twice daily before meals.

Brand names
Humalog Mix25Humalog Mix 75/25
Other names
insulin lispro/insulin lispro protamine 25/7525% insulin lispro and 75% insulin lispro protamine suspension
02

Targets

INSR (Insulin receptor)

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