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A combination of three insulin types used in diabetes management. This combination includes NPH insulin (intermediate-acting), insulin ultralente (long-acting), and insulin lispro (rapid-acting). When mixed, insulin lispro should be drawn into the syringe first to prevent precipitation or turbidity. This combination provides comprehensive glycemic control with rapid onset from lispro for mealtime coverage, intermediate action from NPH, and long-acting basal coverage from ultralente.
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