Drug intelligence / Profile preview

intravenous immunoglobulin + methylprednisolone

Development stage
Preclinical
Lead developer
CSL Behring
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

This is a combination therapy consisting of intravenous immunoglobulin (IVIg) and intravenous methylprednisolone (IVMP). IVIg is a blood product containing pooled immunoglobulins (antibodies) from healthy donors, used to modulate immune responses in various autoimmune and inflammatory diseases. Methylprednisolone is a synthetic corticosteroid with potent anti-inflammatory and immunosuppressive properties. The combination has been studied as an induction treatment for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), where it aims to induce remission more effectively than either agent alone by combining the rapid action of IVIg with the sustained effects of corticosteroids. It has also been investigated in other immune-mediated conditions such as Guillain-Barré syndrome and multisystem inflammatory syndrome in children (MIS-C)[1][3][7][9].

Other names
IVIg + IVMPIVIG plus methylprednisoloneintravenous immunoglobulin and methylprednisolone
02

Targets

FCGR2A (Low affinity immunoglobulin gamma Fc receptor II-a)GR (Glucocorticoid receptor)

Beyond the preview

Go deeper on intravenous immunoglobulin + methylprednisolone.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on intravenous immunoglobulin + methylprednisolone.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call