Drug intelligence / Profile preview

inulin + metronidazole

Development stage
Unknown
Lead developer
Cargill
Modality
Microbiome Therapeutics, Small Molecules
Administration
Oral
01

Overview

This is a combination of inulin, a prebiotic dietary fiber, and metronidazole, an antibiotic and antiprotozoal agent. In clinical research settings, this combination has been studied for its potential to modulate the gut microbiome and improve metabolic parameters in conditions such as non-alcoholic fatty liver disease (NAFLD). The rationale is that short-term administration of metronidazole reduces dysbiotic gut bacteria, followed by inulin supplementation to promote beneficial bacterial growth. Metronidazole acts by disrupting DNA synthesis in anaerobic bacteria and protozoa, while inulin serves as a fermentable substrate for beneficial colonic bacteria[1][2][3][4][5]. This combination does not have an established brand or unique product name on the market but has been used experimentally.

02

Targets

Neuraminidase

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