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iodinated (125 I) human serum albumin
- Development stage
- Unknown
- Lead developer
- Iso-Tex Diagnostics
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
- Administration
- Intravenous
01
Overview
Iodinated (125 I) human serum albumin is a diagnostic radiopharmaceutical consisting of human serum albumin labeled with the radioactive isotope iodine-125. Administered intravenously, it distributes within the vascular compartment (plasma space) and serves as the gold-standard reference method for the determination of total blood and plasma volume via radioactivity dilution. It is primarily indicated for diagnosing and monitoring conditions involving abnormal blood or plasma volume, such as polycythemia and anemia with hemodilution. It is also utilized in clinical research as a reference standard to evaluate novel plasma volume tracers.
- Brand names
- Albumotope I-125Jeanatope
- Other names
- 125I-HSA125I-labeled human albumin125I-labeled human serum albuminalbumin iodinated I-125 serumhuman serum albumin I-125iodinated (125I) human serum albuminiodine-125 labeled human albuminiodine125 labeled human albuminiodine 125 labeled human albuminiodine-125 labeled human serum albuminiodine125 labeled human serum albuminiodine 125 labeled human serum albuminradio-iodinated (125I) human serum albumin
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