isopropyl alcohol + ketorolac tromethamine + lidocaine hydrochloride

This combination is a topical pharmaceutical product containing an antiseptic (isopropyl alcohol), a nonsteroidal anti-inflammatory drug (ketorolac tromethamine), and a local anesthetic (lidocaine hydrochloride). It is primarily used for localized pain management and pre-procedural skin preparation. Lidocaine hydrochloride functions as a local anesthetic by reversibly blocking voltage-gated sodium channels, thereby inhibiting the initiation and conduction of nerve impulses. Ketorolac tromethamine is a potent analgesic and anti-inflammatory agent that works by non-selectively inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, which are responsible for the synthesis of prostaglandins involved in pain and inflammation. Isopropyl alcohol serves as a topical antiseptic, denaturing bacterial proteins to reduce the risk of infection at the application site. This synergistic formulation provides rapid numbing, sustained anti-inflammatory effects, and site sterilization, making it particularly useful for minor surgical procedures and musculoskeletal pain management.

Brand names

Lidocaine-Ketorolac-Isopropyl AlcoholLidocaine Hydrochloride and Ketorolac Tromethamine in Isopropyl Alcohol

Other names

L-K-I Topical SolutionKetorolac-Lidocaine-Isopropyl Alcohol Solution