Drug intelligence / Profile preview

isopropyl alcohol + moroctocog alfa

Development stage
Unknown
Lead developer
Pfizer
Modality
Small Molecules, Recombinant Proteins and Enzymes
Administration
Intravenous, Topical
01

Overview

**isopropyl alcohol + moroctocog alfa** refers to the co-packaged presentation associated with **Xyntha**, containing recombinant factor VIII **moroctocog alfa** for intravenous replacement therapy in hemophilia A together with **isopropyl alcohol** supplied as an alcohol prep component for skin antisepsis during administration. The therapeutically active disease-treating component is moroctocog alfa, a recombinant antihemophilic factor that replaces deficient factor VIII and restores intrinsic coagulation by functioning as a cofactor for factor IXa in the activation of factor X, thereby improving thrombin generation and clot formation in patients with congenital factor VIII deficiency. Xyntha was developed by Wyeth and is marketed by Pfizer for on-demand control of bleeding, perioperative management, and routine prophylaxis in adults and children with hemophilia A; it is not indicated for von Willebrand disease. Isopropyl alcohol in this context is not the systemic therapeutic agent for hemophilia but an administration-associated antiseptic component of the product presentation.

Brand names
Xyntha
Other names
antihemophilic factor recombinant + isopropyl alcoholmoroctocog alfa + isopropyl alcohol
02

Targets

Coagulation Factor IXaF10 (Factor Xa)BB-031 (Von Willebrand factor)F8 (Coagulation Factor VIIIa)

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