Isosorbide oral solution (Lunan Better Pharmaceutical)

Isosorbide oral solution is a small molecule osmotic diuretic being developed by Lunan Better Pharmaceutical Co., Ltd. for the treatment of Meniere's disease. The drug's primary mechanism of action involves reducing endolymphatic hydrops, a pathological buildup of fluid in the inner ear that is a hallmark of Meniere's disease. By acting as an osmotic agent, isosorbide facilitates the withdrawal of excess fluid from the endolymphatic space. While isosorbide has a long history of use for this indication in countries like Japan, this specific formulation is undergoing a formal Phase II/III clinical program to establish its efficacy and safety profile in patients with unilateral Meniere's disease.

Brand names

IsobideIsmotic

Other names

Isosorbide oral solutionisosorbide