ivermectin + permethrin

ivermectin + permethrin-University Ghent-scabies refers to the comparative clinical evaluation of oral ivermectin and topical permethrin for the treatment of scabies, a skin infestation caused by the mite *Sarcoptes scabiei*. This specific context originates from a Phase 2 clinical trial (NCT00300716) sponsored by University Ghent, which utilized a double-blind, double-dummy design to assess whether a single administration of either agent provided sufficient efficacy. Ivermectin is an anthelmintic small molecule that induces parasite paralysis by activating glutamate-gated chloride channels. Permethrin is a synthetic pyrethroid neurotoxin that disrupts voltage-gated sodium channels, leading to prolonged depolarization and death of the mite.

Other names

Ivermectin vs Permethrin for Scabies