Drug intelligence / Profile preview

Japanese encephalitis inactivated vaccine (Vero cells)

Development stage
Unknown
Lead developer
Shandong Hengye Biotechnology
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Japanese encephalitis inactivated vaccine (Vero cells) is a purified, inactivated viral vaccine developed for the prevention of Japanese encephalitis (JE). The vaccine is produced by propagating the Japanese encephalitis virus in Vero cell cultures, followed by purification and inactivation, typically using formaldehyde. This specific candidate, developed by Shandong Hengye Biotechnology, has undergone Phase III clinical testing in China to evaluate its safety and immunogenicity in healthy infants aged 6-11 months. The vaccine aims to provide a safer and more consistent alternative to older mouse brain-derived vaccines by utilizing a standardized cell culture production platform.

Other names
purified Japanese encephalitis inactivated vaccine (Vero cells)JE-IV (Vero cells)purified inactivated Japanese encephalitis vaccine (Vero cells)
02

Targets

JEV prM/E (Japanese encephalitis virus prM/E antigen)

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