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Japanese encephalitis vaccine + hepatitis A vaccine

Development stage
Unknown
Lead developer
Valneva
Modality
Whole Inactivated Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

This entry refers to the concurrent administration of two separate vaccines—Japanese encephalitis (JE) vaccine and hepatitis A (HepA) vaccine. The JE vaccine is an inactivated viral vaccine used to prevent infection by the Japanese encephalitis virus, primarily indicated for travelers to endemic areas and laboratory workers. It works by inducing the body’s immune system to produce protective antibodies against the JE virus[7]. The HepA vaccine is also an inactivated viral preparation that induces immunity against hepatitis A infection. Both vaccines are typically administered as intramuscular injections. Clinical studies have shown that co-administration of these two vaccines does not significantly interfere with their safety or immunogenicity profiles; each maintains its effectiveness when given at different injection sites during the same visit[1][5]. There are no known combination products containing both antigens; rather, this refers to simultaneous administration of individual licensed products.

Brand names
IXIARO
Other names
JE-VC + HepAinactivated Japanese encephalitis virus vaccine + inactivated hepatitis A virus vaccine
02

Targets

JEV prM/E (Japanese encephalitis virus prM/E antigen)Hepatitis A virus capsid protein

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