Jena DM + metformin

Jena DM + metformin is a combination therapy used in the management of type 2 diabetes mellitus. Jena DM is a licensed herbal formulation in Uganda, primarily containing extracts of Cymbopogon citratus (lemongrass), and is used as a complementary therapy alongside standard oral hypoglycemic agents such as metformin. Metformin is a biguanide antihyperglycemic agent that decreases hepatic glucose production, increases insulin sensitivity, and reduces appetite via GDF15 secretion. The combination aims to improve glycemic control and may have additive effects on weight reduction; however, clinical studies indicate that while Jena DM does not significantly reduce HbA1c when added to metformin, it can lead to modest weight loss but also increases the risk of adverse events such as dizziness and epigastric pain[1][6]. The mechanism of action for Jena DM likely involves phytochemicals with potential hypoglycemic activity from Cymbopogon citratus, though precise molecular targets are not fully characterized.

Other names

Jena DM + metformin