Drug intelligence / Profile preview

Jian'er Qiangshen

Development stage
Preclinical
Administration
Topical
01

Overview

Jian'er Qiangshen (JEQS) is a Traditional Chinese Medicine (TCM) formulation, typically prepared as an ointment or paste, used for the treatment of bronchial asthma. It exerts its therapeutic effects through a multi-target mechanism that includes the inhibition of lung inflammation and the modulation of intestinal microbiota. Specifically, JEQS has been shown to reduce levels of inflammatory cytokines such as IFN-γ, IL-4, IL-5, and IL-13. Its primary active constituents include α-linolenic acid, 9-oxononanoic acid, inosine, linoleic acid, and amygdalin. Research indicates it targets key proteins such as AKT1, IL-6, TNF, and MAPK3, while also promoting a healthy balance of gut bacteria like Proteobacteria and Actinobacteria.

Brand names
Jian'er Qiangshen
Other names
JEQSJian'er Qiangshen ointmentJian'er Qiangshen Gao
02

Targets

IL-6 (Interleukin 6)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)MAPK3 (Mitogen-activated protein kinase 1)

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