Drug intelligence / Profile preview

jian-pi bu-shen jie-du-fang (Xiyuan Hospital)

Development stage: Unknown
Lead developer: Xiyuan Hospital
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Jian-pi bu-shen jie-du-fang is a Traditional Chinese Medicine (TCM) decoction developed by Xiyuan Hospital of the China Academy of Chinese Medical Sciences. It is formulated based on the TCM principles of strengthening the spleen (Jian-pi), tonifying the kidney (Bu-shen), and clearing toxins (Jie-du). The formula is primarily investigated as an adjuvant or combination therapy for advanced malignancies, specifically stage IV colorectal cancer. In clinical trial ChiCTR1900022673, it is evaluated in combination with low-dose apatinib (a VEGFR-2 inhibitor) and S-1 (tegafur-gimeracil-oteracil) for patients who are intolerant to or have failed conventional chemotherapy. The decoction aims to improve patient quality of life, reduce treatment-related toxicity, and potentially enhance the efficacy of anti-angiogenic and cytotoxic agents.

Other names: Jian-Pi Bu-Shen Jie-Du-Fang decoctionJianpi Bushen Jiedu formula

Beyond the preview

Go deeper on jian-pi bu-shen jie-du-fang (Xiyuan Hospital).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on jian-pi bu-shen jie-du-fang (Xiyuan Hospital).

Explore the full profile