Drug intelligence / Profile preview

Jincao (Beijing Konruns Pharmaceutical Co., Ltd.)

Development stage
Unknown
Lead developer
Beijing Konruns Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Jincao (Jincao Tablet) is an innovative botanical drug candidate composed of total iridoid glycosides extracted from the medicinal herb *Siegesbeckia orientalis* (Xi Xian Cao). Developed by Beijing Konruns Pharmaceutical in collaboration with the Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, it is specifically indicated for the treatment of chronic pelvic pain (CPP) resulting from the sequelae of pelvic inflammatory disease (PID). The drug functions through anti-inflammatory and analgesic pathways characteristic of iridoid glycosides. It is currently in Phase III clinical development in China, where its efficacy and safety are being evaluated in adult women, with pain reduction measured by the Visual Analogue Scale (VAS) as a primary endpoint.

Brand names
Jincao TabletJincao pian
Other names
total iridoid glycosides of Siegesbeckia orientalisXi Xian Cao extract
02

Targets

ESR1 (ERα)

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