Drug intelligence / Profile preview

Juice Plus+

Development stage
Unknown
Lead developer
Juice Plus+
Modality
Small Molecules
Administration
Oral
01

Overview

Juice Plus+ is a whole-food-based nutritional supplement containing concentrated fruit and vegetable powders. It is typically provided as encapsulated blends (Orchard, Garden, and Berry) manufactured by The Juice Plus+ Company (formerly NSA International). The product is designed to provide phytochemicals and micronutrients from a variety of plants, including apples, oranges, carrots, and broccoli. Clinical research has investigated its effects on systemic inflammation (reducing TNFα), lipid profiles (lowering total and LDL cholesterol), and metabolic health in overweight or obese adults. It has also been studied for its impact on biomarkers in cancer patients. As a dietary supplement, it is categorized as Generally Recognized as Safe (GRAS) by the FDA.

Brand names
Juice Plus+
Other names
F&V juice concentrateencapsulated fruit and vegetable juice concentrateOrchard, Garden and Berry Blends
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)PMVK (Phosphomevalonate kinase)26S proteasomeTNFA (Tumor necrosis factor alpha (soluble))

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