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JWXYJN + sertraline
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
JWXYJN + sertraline is a combination therapy consisting of Jia Wei Xiao Yao Jiaonang (a traditional Chinese medicine herbal capsule) and sertraline (a selective serotonin reuptake inhibitor antidepressant). This combination has been studied for the treatment of mild to moderate major depressive disorder. - **Jia Wei Xiao Yao Jiaonang** is a multi-herbal formulation used in traditional Chinese medicine, often prescribed for mood disorders such as depression and anxiety. Its mechanism is not fully elucidated but may involve modulation of neurotransmitter systems and anti-inflammatory effects. - **Sertraline** is a well-established pharmaceutical antidepressant that works by selectively inhibiting the reuptake of serotonin in the brain, thereby increasing its availability and improving mood symptoms[2]. The combination aims to leverage both the traditional multi-targeted approach of herbal medicine with the established efficacy of modern pharmacotherapy.
- Other names
- Jia Wei Xiao Yao Jiaonang + sertralineJia Wei Xiao Yao Capsule + sertraline
02
Targets
SERT (Sodium-dependent serotonin transporter)
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