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Three-chamber bags (3CB) from Fresenius Kabi, most notably marketed under the brand names **Kabiven** and **SmofKabiven**, are all-in-one parenteral nutrition systems designed for the treatment of malnutrition. These products consist of a plastic bag with three separate compartments containing amino acids (with electrolytes), a dextrose solution, and a lipid emulsion. The compartments are separated by peel-seals that are broken and mixed immediately prior to intravenous administration. This design ensures the stability of the individual components during storage while providing a convenient, standardized, and sterile 'all-in-one' mixture for the patient. Kabiven utilizes a soybean oil-based lipid emulsion, whereas SmofKabiven contains SMOFlipid, a four-oil blend (soybean, medium-chain triglycerides, olive, and fish oil) designed to provide a more balanced fatty acid profile. Clinical studies comparing 3CBs to hospital-compounded parenteral nutrition have demonstrated that these standardized bags can reduce the risk of bloodstream infections and medication errors.
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