Drug intelligence / Profile preview

Kan Jang + curcumin

Development stage
Unknown
Lead developer
Swedish Herbal Institute
Modality
Small Molecules
Administration
Oral
01

Overview

**Kan Jang + curcumin** is a combination of natural plant extracts being investigated for the treatment of the common cold and upper respiratory tract infections. Kan Jang is a well-established herbal medicinal product containing standardized extracts of *Andrographis paniculata* (SHA-10) and *Eleutherococcus senticosus* (SHE-3), originally developed by the Swedish Herbal Institute. Curcumin is a polyphenolic compound derived from turmeric (*Curcuma longa*) with potent anti-inflammatory and antioxidant properties. The combination is being evaluated by Procter & Gamble in a Phase 3 clinical trial (EudraCT 2005-005207-42) to assess its efficacy in reducing the severity and duration of cold symptoms compared to placebo, with an active control arm of ibuprofen plus chlorphenamine maleate.

Other names
Kan Jang plus curcuminKan Jang and curcumin
02

Targets

IKK complexNFKB1 (NF-κB1)EP300 (Histone acetyltransferase p300)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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