kanamycin + metronidazole

Kanamycin + metronidazole is a synergistic antibiotic combination that demonstrates enhanced efficacy against various bacterial infections. Kanamycin is an aminoglycoside that prevents bacterial protein synthesis by binding to 16S rRNA of the 30S ribosomal subunit, while metronidazole is reduced to cytotoxic compounds that cause DNA damage in bacteria. When combined, these antibiotics show significant synergy with drastically reduced minimum inhibitory concentrations, allowing for lower doses while maintaining or enhancing antimicrobial activity. This combination is effective against a wide spectrum of pathogens including gram-positive and gram-negative bacteria, anaerobic bacteria, and certain protozoa.

Brand names

General Trio Powder

Other names

super drugsuper cure