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ketamine + mometasone furoate
- Development stage
- Unknown
- Lead developer
- Pfizer
- Modality
- Small Molecules
- Administration
- Topical, Intranasal, Inhalation, Intravenous, Intramuscular
01
Overview
Ketamine + mometasone furoate is a combination of two pharmaceutical agents. Ketamine is a rapid-acting general anesthetic and analgesic that works primarily as an antagonist of the N-methyl-D-aspartate (NMDA) receptor. It produces dissociative anesthesia and profound analgesia[8]. Mometasone furoate is a potent synthetic corticosteroid with anti-inflammatory properties; it acts mainly by binding to the glucocorticoid receptor to modulate gene expression and suppress inflammatory responses[1][5]. This combination may be used off-label in compounded topical or intranasal formulations for conditions where both local anesthesia/analgesia and anti-inflammatory effects are desired.
- Brand names
- DuleraElocomRyaltrisSinuvaZenhale
02
Targets
NMDAR (Glutamate receptor ionotropic, NMDA)PR (Progesterone receptor)GR (Glucocorticoid receptor)
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