ketoconazole + triamcinolone acetonide

SebDuo is a compounded topical combination of the imidazole antifungal ketoconazole (8%) and the mid-potent corticosteroid triamcinolone acetonide (0.4%). Formulated as a concentrate, it is designed to be mixed with a patient's regular shampoo for the treatment of seborrheic dermatitis of the scalp. Ketoconazole acts by inhibiting fungal lanosterol 14-alpha-demethylase, thereby reducing the population of *Malassezia* yeast on the scalp, which is a key driver of seborrheic dermatitis. Triamcinolone acetonide acts as a glucocorticoid receptor agonist to provide rapid anti-inflammatory and antipruritic effects, relieving itching and redness. Developed by MedCara, SebDuo is compounded and distributed under prescription by licensed pharmacies such as NuCara Pharmacy.

Brand names

SebDuo

Other names

ketoconazole and triamcinolone acetonideketoconazole/triamcinolone acetonide