Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
ketorolac + dexamethasone
- Development stage
- Unknown
- Lead developer
- Roche
- Modality
- Small Molecules
- Administration
- Ophthalmic, Intravenous, Intramuscular
01
Overview
Ketorolac + dexamethasone is a fixed-dose combination of two active pharmaceutical ingredients: ketorolac, a non-steroidal anti-inflammatory drug (NSAID), and dexamethasone, a synthetic corticosteroid. This combination is primarily used in ophthalmology for the treatment of inflammatory conditions such as bacterial eye infections and postoperative ocular inflammation. Ketorolac works by inhibiting cyclooxygenase enzymes (COX), thereby reducing prostaglandin synthesis responsible for pain and inflammation. Dexamethasone acts as an anti-inflammatory and immunosuppressant by modulating gene expression to suppress pro-inflammatory cytokines and mediators. Together, they provide synergistic effects in reducing pain, redness, swelling, and other symptoms associated with ocular inflammation or infection[8]. The combination has also been studied for use in acute pain management (such as renal colic) where it may reduce opioid requirements and improve control of nausea[5][6][9].
- Brand names
- KetrodexTolar-LXPainlok PlusBioket LDIrolacNeriket DKetolac-LDEylac-DKetopar D
- Other names
- ketorolac + dexamethasone
02
Targets
GR (Glucocorticoid receptor)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
Beyond the preview
Go deeper on ketorolac + dexamethasone.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on ketorolac + dexamethasone.