ketorolac + isopropyl alcohol + lidocaine

This is a **combination pharmaceutical product** composed of ketorolac (a nonsteroidal anti-inflammatory drug), isopropyl alcohol (an antiseptic/disinfectant), and lidocaine (a local anesthetic). Ketorolac acts by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby blocking prostaglandin synthesis to produce analgesic and anti-inflammatory effects[7]. Lidocaine blocks voltage-gated sodium channels in neuronal membranes, preventing pain signal transmission[8]. Isopropyl alcohol serves primarily as a vehicle and antiseptic but does not contribute a pharmacological effect relevant to analgesia[9]. This combination is used for **local injection or regional anesthesia** where rapid and prolonged pain control is desired, often in procedures such as musculoskeletal biopsies and minor surgeries, with evidence showing superior pain control compared to lidocaine alone during the early postoperative period[1][3].

Brand names

Acunistat-30Acunistat30Acunistat 30Acunistat-60Acunistat60Acunistat 60

Other names

ketorolac tromethamine + isopropyl alcohol + lidocaine hydrochloride