Drug intelligence / Profile preview

ketorolac + isopropyl alcohol + lidocaine + povidone-iodine

Development stage
Unknown
Lead developer
Roche
Modality
Small Molecules
Administration
Infiltration, Intramuscular, Intravenous, Perineural, Topical
01

Overview

This is a combination drug product containing **ketorolac**, **isopropyl alcohol**, **lidocaine**, and **povidone-iodine**. - **Ketorolac** is a nonsteroidal anti-inflammatory drug (NSAID) that acts as an analgesic and anti-inflammatory primarily by inhibiting cyclooxygenase (COX-1 and COX-2) and subsequently prostaglandin synthesis, reducing pain and inflammation. - **Lidocaine** is a local anesthetic that stabilizes neuronal membranes by inhibiting voltage-gated sodium channels, preventing the initiation and transmission of nerve impulses and thus providing local anesthesia. - **Isopropyl alcohol** is an antiseptic and disinfectant often used for skin cleansing prior to procedures. - **Povidone-iodine** is a topical antiseptic, providing broad-spectrum antimicrobial activity through free iodine release and is used to reduce the risk of infection at the site of application. This combination is intended for procedural or surgical settings where pain control, anesthesia, and infection prophylaxis are required, such as wound care, minor surgery, or biopsy procedures[1][2][3][7][8][9]. The product does not correspond to a widely used single brand or unique combination drug but reflects components sometimes co-formulated in procedural kits.

Brand names
Ketorocaine L Kit
Other names
isopropyl alcohol + povidone-iodine + ketorolac tromethamine + lidocaine hydrochlorideKetorolac Tromethamine, Lidocaine Hydrochloride, Povidone-Iodine, and Isopropyl Alcohol Kit
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NaV (Voltage-gated sodium channels)PGHS-1 (Prostaglandin G/H Synthase 1)

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