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l-ascorbic acid + chitosan

Development stage
Unknown
Modality
Small Molecules, Hydrogel Systems → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Oral, Topical
01

Overview

l-ascorbic acid + chitosan is a combination of L-ascorbic acid (vitamin C), a water-soluble antioxidant vitamin, and chitosan, a biocompatible polysaccharide derived from the shells of crustaceans. This combination has been studied for its synergistic effects in various applications including weight management, neuroprotection, wound healing materials, and cosmetic formulations. Mechanistically, L-ascorbic acid provides antioxidant activity and may enhance fat metabolism or reduce oxidative stress. Chitosan acts as a dietary fiber with fat-binding properties and also serves as a carrier or matrix for controlled release of active agents. The combination has shown enhanced reduction in body weight gain compared to either agent alone in both animal models and human studies[1]. In pharmaceutical technology and biomaterials research, the l-ascorbic acid-chitosan complex demonstrates improved stability over free vitamin C while retaining strong antioxidant capacity; it also exhibits moisturizing properties and antibacterial activity[2][3][7]. Applications include dietary supplements for obesity/weight loss management[1], neuroprotective supplements[3], functional hydrogels for wound healing or dental use[5], and cosmetic products.

Other names
ascorbic acid + chitosanvitamin C + chitosanCSVC complexchitosan-vitamin C complex

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