Drug intelligence / Profile preview

L.M.X.4 cream + saline injection

Development stage: Unknown
Lead developer: Ferndale Laboratories
Modality: Small Molecules
Administration: Topical, Subcutaneous

Overview

L.M.X.4 is a topical anesthetic cream containing 4% lidocaine, used for local analgesia. In a clinical trial conducted by Vanderbilt University Medical Center (NCT04766684), it is being studied in combination with a saline injection (delivered via the J-Tip needle-free system) as a comparator arm for pain management in infants undergoing percutaneous Achilles tenotomy for clubfoot. Lidocaine works by blocking voltage-gated sodium channels, preventing the conduction of nerve impulses and providing localized pain relief. This specific protocol evaluates the efficacy of the topical cream against needle-free lidocaine injections to optimize pain control in neonatal orthopedic procedures.

Brand names: L.M.X.4
Other names: LMX4LMX-4LMX 4Lidocaine 4% creamL.M.X.4 cream with J-Tip saline injectionLMX4 + saline

Targets

NaV (Voltage-gated sodium channels)

Beyond the preview

Go deeper on L.M.X.4 cream + saline injection.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on L.M.X.4 cream + saline injection.

Explore the full profile