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Drug intelligence / Profile preview
lactase + ligilactobacillus salivarius DSM 34078
- Development stage
- Preclinical
- Lead developer
- Johnson & Johnson
- Modality
- Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Therapeutic Enzymes → Recombinant Proteins and Enzymes
- Administration
- Oral
01
Overview
This is a combination product containing **lactase**, an exogenous enzyme that hydrolyzes lactose into glucose and galactose to facilitate lactose digestion, and **Ligilactobacillus salivarius DSM 34078**, a specific strain of probiotic bacteria. The combination is designed to improve **lactose digestion** and reduce gastrointestinal symptoms in individuals with lactose intolerance, potentially providing more prolonged benefit compared to lactase enzyme alone. Lactase acts directly by enzymatic cleavage of dietary lactose, while L. salivarius DSM 34078 is thought to support lactose digestion through probiotic colonization, production of lactase, and modulation of the gut microbiome. This combination targets both the immediate enzymatic breakdown of lactose and the enhancement of gut microbiota's lactase activity[1][3][6].
- Other names
- lactase + lactobacillus salivarius DSM 34078lactase + L. salivarius DSM 34078
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