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lactated Ringer's solution + hydroxyethyl starch
- Development stage
- Unknown
- Lead developer
- Cukurova University
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Intravenous
01
Overview
Lactated Ringer's solution + hydroxyethyl starch refers to the use of crystalloid and colloid intravenous fluids, specifically evaluated in clinical research conducted by Cukurova University. This combination or comparison is primarily studied for the prevention and management of hypotension induced by spinal anesthesia, particularly during cesarean sections. Lactated Ringer's solution is an isotonic crystalloid that provides immediate intravascular volume expansion and electrolyte replacement. Hydroxyethyl starch (HES) is a synthetic colloid that increases plasma oncotic pressure, allowing for more sustained volume expansion compared to crystalloids. The clinical focus is on determining the optimal fluid resuscitation strategy to minimize the need for vasopressors like ephedrine and to maintain maternal hemodynamics.
- Other names
- crystalloid + colloidLactated Ringer's + HESLR + HES
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