Drug intelligence / Profile preview

lactobacillus delbrueckii + lactobacillus fermentum

Development stage
Unknown
Lead developer
Mayoly Spindler
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral, Vaginal
01

Overview

**Lactobacillus delbrueckii + lactobacillus fermentum** is an oral probiotic or postbiotic antidiarrheal combination composed of two Lactobacillus strains commonly referred to together as **Lactobacillus LB** and marketed as **Lacteol Fort**. It has been used primarily for diarrhea-related gastrointestinal disorders and has also been studied in irritable bowel syndrome with diarrhea predominance. Its proposed activity is not a single receptor-target interaction but a microbiome-directed effect that includes antagonism of enteric pathogens, protection of the intestinal epithelial surface, restoration of microbial balance, and local immunomodulatory effects in the gut. Public sources verify the exact combination in clinical research and marketed-product contexts, including ClinicalTrials.gov records for IBS-D and branded Lactéol product pages describing Lactobacillus LB as the active digestive postbiotic ingredient.

Brand names
Lacteol FortLactéol Fort
Other names
Lactobacillus LBLBlactobacillus delbrueckii + lactobacillus fermentum

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