lactobacillus gasseri + lactobacillus crispatus

Lactobacillus gasseri + Lactobacillus crispatus is a combination of two key commensal bacterial species used as a live biotherapeutic product (LBP) to support and restore the human vaginal and gastrointestinal microbiota. These Gram-positive, lactic acid-producing bacteria are dominant members of a healthy vaginal ecosystem, where they play a crucial role in preventing dysbiosis. Their therapeutic effect is mediated through the acidification of the local environment via lactic acid production, the secretion of inhibitory substances such as hydrogen peroxide and bacteriocins, and the competitive occupation of epithelial binding sites, which prevents the colonization and overgrowth of pathogens like Gardnerella vaginalis and Candida species. This combination is primarily investigated for the treatment and prevention of bacterial vaginosis (BV), recurrent urinary tract infections (UTIs), and other urogenital infections.

Brand names

VagiBiomFloraFemme

Other names

Lactobacillus gasseri and Lactobacillus crispatusL. gasseri + L. crispatusLactobacillus gasseri and Lactobacillus crispatus combination