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lactobacillus paracasei + lactobacillus casei 431 + lactobacillus fermentum PCC
- Development stage
- Unknown
- Lead developer
- Novonesis
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
This combination is a multi-strain probiotic formulation designed to support immune system function and gastrointestinal health. It features two clinically studied trademarked strains: **Lactobacillus casei 431** (a strain of *Lactobacillus paracasei*) and **Lactobacillus fermentum PCC**. *L. casei 431* is recognized for its ability to stimulate the immune response, particularly by increasing secretory immunoglobulin A (sIgA) levels and reducing the duration of upper respiratory tract infections. *L. fermentum PCC* is a resilient strain isolated from human gut flora that survives gastric transit to colonize the intestine, where it modulates cytokine production and supports the body's natural defenses. The addition of generic *Lactobacillus paracasei* (often the Lpc-37 strain in commercial blends) further enhances the formulation's ability to maintain a healthy microbiome and support intestinal barrier integrity.
- Brand names
- Life-Space Immune Support Probiotic
- Other names
- Lactobacillus paracasei + Lactobacillus casei 431 + Lactobacillus fermentum PCCProbiotic Immune Formula
02
Targets
sIgA (Secretory immunoglobulin A)TLR2 (Toll-like Receptor 2)
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