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lactobacillus paracasei NCC2461 + streptococcus thermophilus + lactobacillus delbrueckii subsp. bulgaricus
- Development stage
- Unknown
- Lead developer
- Nestlé
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
This probiotic combination consists of the specific strain *Lactobacillus paracasei* NCC2461 (also known as ST11) along with the standard yogurt starter cultures *Streptococcus thermophilus* and *Lactobacillus delbrueckii* subsp. *bulgaricus*. Developed primarily by Nestlé, this blend is utilized in fermented milk products and dietary supplements to support gastrointestinal health and modulate the immune system. *L. paracasei* NCC2461 has been extensively researched for its immunomodulatory properties, including its ability to reduce skin sensitivity, improve intestinal barrier function, and potentially alleviate symptoms of atopic dermatitis. The inclusion of *S. thermophilus* and *L. bulgaricus* serves both a functional role in the fermentation of the delivery vehicle (e.g., yogurt) and a synergistic probiotic role in maintaining a healthy gut microbiota.
- Other names
- Lactobacillus paracasei ST11 + Streptococcus thermophilus + Lactobacillus bulgaricusL. paracasei NCC2461 + S. thermophilus + L. bulgaricus
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