lactose-University of Wisconsin, Madison

Lactose is utilized as an inactive placebo control in clinical research conducted by the University of Wisconsin-Madison, specifically within studies investigating human cerebral blood flow (CBF) regulation. In these mechanistic trials, such as those examining sex differences and the effects of hypoxic or hypercapnic stress (e.g., NCT02936687), lactose is administered in pill form to serve as a comparator against active pharmacological agents like indomethacin or hormonal modulators. This experimental design allows researchers to isolate the physiological effects of active interventions on cerebrovascular regulation using advanced MRI techniques in healthy volunteers and specific patient populations.

Other names

lactose