lambda-bis(2,2'-bipyridine)-(5-methyl-2-2'-bipyridine)-C9-adamantane ruthenium (II)

Lambda-bis(2,2'-bipyridine)-(5-methyl-2-2'-bipyridine)-C9-adamantane ruthenium (II) is a ruthenium(II) coordination complex featuring bipyridine and adamantane ligands. This compound belongs to a class of ruthenium complexes extensively investigated for their potential biological activities, particularly as anticancer agents. Its mechanism of action is thought to involve interactions with DNA, leading to DNA damage, and the induction of oxidative stress through the generation of reactive oxygen species (ROS). Some related ruthenium complexes demonstrate enhanced cytotoxicity upon photoactivation, suggesting a potential role in photochemotherapy. The presence of the bulky adamantane group may influence its pharmacokinetic properties and cellular interactions.

Other names

LAMBDA-BIS(2,2'-BIPYRIDINE)-(5-METHYL-2-2'-BIPYRIDINE)-C9-ADAMANTANE RUTHENIUM (II)RefChem:798400DB01663DB-01663DB 01663bis[1H,1'H-2,2'-bipyridinato(2-)-kappa~2~N~1~,N~1'~][9-(4'-methyl-1H,1'H-2,2'-bipyridin-4-yl-kappa~2~N~1~,N~1'~)-N-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]nonanamidato(2-)]ruthenium(2+)