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lamivudine + abacavir + tenofovir disoproxil fumarate + lopinavir + ritonavir
- Development stage
- Unknown
- Lead developer
- Cipla
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination of five antiretroviral medications used in the treatment of HIV infection. This combination includes two nucleoside reverse transcriptase inhibitors (lamivudine and abacavir), one nucleotide reverse transcriptase inhibitor (tenofovir disoproxil fumarate), and two protease inhibitors (lopinavir and ritonavir, with ritonavir serving as a pharmacokinetic enhancer for lopinavir).
02
Targets
Human immunodeficiency virus type 1 reverse transcriptaseHLA-B*57:01 (Human leukocyte antigen B*57:01)HBV Pol (Hepatitis B virus polymerase)CYP3A4 (Cytochrome P450 3A4)CYP3A5 (Cytochrome P450 family 3 subfamily A member 5)PR (Progesterone receptor)
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