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lansoprazole + amoxicillin + metronidazole
- Development stage
- Unknown
- Lead developer
- Takeda
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A triple therapy combination used for the treatment and eradication of Helicobacter pylori infection, particularly in cases of duodenal ulcers. This regimen combines lansoprazole (a proton pump inhibitor that reduces gastric acid secretion) with two antibiotics (amoxicillin and metronidazole) to effectively eliminate H. pylori bacteria. This combination is particularly valuable in areas with high prevalence of clarithromycin resistance.
02
Targets
PBP (Penicillin-binding protein family)NeuraminidaseATP4A (Potassium–transporting ATPase alpha chain 1)
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