lansoprazole + methotrexate + naproxen

This is a combination of three drugs commonly used in the management of rheumatoid arthritis and related conditions. **Lansoprazole** is a proton pump inhibitor (PPI) that reduces stomach acid production to protect against NSAID-induced gastric ulcers. **Methotrexate** is an antimetabolite and disease-modifying antirheumatic drug (DMARD) that inhibits dihydrofolate reductase, reducing inflammation and slowing disease progression. **Naproxen** is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes, providing analgesic and anti-inflammatory effects[9][10]. The combination may be used together for patients with rheumatoid arthritis who require both pain relief/anti-inflammatory therapy (naproxen), disease modification (methotrexate), and gastroprotection from NSAID-induced ulcers (lansoprazole)[9][10].

Other names

lansoprazole, methotrexate, and naproxen combination