Drug intelligence / Profile preview

lanthanum(III) cation

Development stage: Unknown
Lead developer: Assertio
Modality: Inorganic Nanoparticles → Nanoparticles → Drug Delivery Systems, Small Molecules
Administration: Oral

Overview

Lanthanum(III) cation is a rare earth metal ion with the chemical formula La³⁺. It functions as a phosphate binder and is used in biochemical research to block the activity of divalent cation channels, especially calcium channels. In clinical applications, lanthanum compounds like lanthanum carbonate are used to reduce serum phosphate levels in patients with end-stage renal disease by forming insoluble complexes with phosphate in the gastrointestinal tract, preventing its absorption.

Other names: Lanthanum cation (3+)Lanthanum ionLanthanum, ion (La3+)lanthanum(3+) ionLanthanum(3+) ionslanthanum(III) cation

Targets

CaV (Voltage-gated calcium channel protein complex)

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