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LCP-tacrolimus + mycophenolate mofetil
- Development stage
- Unknown
- Lead developer
- Veloxis Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
This combination involves **LCP-tacrolimus** (a once-daily formulation of tacrolimus) and **mycophenolate mofetil** (MMF), both used as immunosuppressants to prevent organ rejection in transplant patients. Tacrolimus is a calcineurin inhibitor that suppresses the immune system by inhibiting the production of interleukin-2, while MMF inhibits inosine monophosphate dehydrogenase, reducing lymphocyte proliferation. This combination is often used in kidney transplantation.
02
Targets
IMPDH (Inosine-5'-monophosphate dehydrogenase 1)CN (Calcineurin)
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